Keto is short for ketogenic. The ketogenic diet is a high-fat, adequate protein, and low-carbohydrate diet. A standard ketogenic diet follows a ratio of approximately 75% of calories from fat; 20% from protein; and 5% from carbohydrates. The ketogenic way of eating helps promote ketosis, the natural metabolic state when your body relies on ketones for fuel instead of glucose. Your body can transition to ketosis when you replace carbs with fat and protein. Medically, the keto diet ─ which is based on the principle of nutritional ketosis ─ has been used as medical nutrition therapy (MNT) to address conditions such as Angelman Syndrome and epilepsy. Other research has been examining potential new applications, such as helping people with diabetes, cardiovascular disease, and obesity. Scientists have been pointing to possible use in conditions such as Alzheimer’s disease, amyotrophic lateral sclerosis (ALS), autism, brain cancer, headache, neurotrauma, pain, Parkinson’s disease, and sleep disorders.

The diet reprograms the body to burn fats rather than carbohydrates. Normally, carbohydrates ─ important in fueling brain function ─ contained in food are converted into glucose. This glucose is transported around the body. With few carbohydrates remaining in the diet, the liver converts fat into fatty acids and ketone bodies. The ketones are able to help the brain replace glucose as an energy source.

A ketogenic diet is medically used for certain conditions and non-medically used to support weight loss and heart health. Getting the majority of calories from fat forces the body to use different energy pathways. Instead of using carbs for energy, the body burns fat, entering a state called ketosis. Keto has been emerging as a good nutritional alternative compared to other diets, such as Atkins or low-carb.

Ketosis is a metabolic state that occurs when your body begins drawing its energy primarily through ketones rather than glucose. Ketones can readily be converted into energy when transported to your body through the bloodstream. They are formed in your liver and are derived from fat, a process which accelerates when the body has few other sources of energy (like carbohydrates).Most people can enter ketosis within one to two weeks of adopting a ketogenic diet. It can be difficult to pinpoint the exact point you enter ketosis, but if you are maintaining a healthy caloric count while keeping your carb intake to a minimum (20 grams or less to start is recommended), then your body will enter this state when it runs out of glycogen stores. You can also measure your ketone levels if you want a more precise understanding.

Yes! The keto diet is safe for medical and non-medical uses. In fact, several studies show that ketogenic medical nutrition therapy can even be used for neurological diseases, like epilepsy. For health support, a keto diet can help people achieve their weight loss goals.

Research shows that a long-term ketogenic diet is safe and effective. It is recommended that you treat the keto diet as a long-term or permanent lifestyle change versus a temporary diet.

The term “keto flu,” also known as the carb flu, was coined to describe the symptoms experienced when starting the ketogenic diet. It doesn’t affect everyone, but those who are impacted typically experience mild “flu-like” symptoms ─ fever, headache, body ache, fatigue, and chills. It is believed that these symptoms may be caused when the body transitions from a carb-burning state to a fat-burning state, or when toxins are leaving the body.  

The best way to be successful on the keto diet is to stick to consuming only keto-approved foods and ingredients.

We recommend following these two principles:

  1. Eat mostly protein-dense and fiber-rich whole foods
  2. Eliminate all calorically-dense processed foods from your diet

Track your health stats.

One of the best ways to stay on track is by using a calorie tracking app and a scale. By using both, you will know what you’re consuming and how you need to adjust your diet to achieve long-term success. On the keto diet, some people also track their success by measuring their ketones with ketone meters. Measuring your ketone levels can tell you whether or not you’re in ketosis, which is when your body is in fat-burning mode.

Prepare for the effects of dietary changes.

Going from a diet that doesn’t limit carbs to a ketogenic diet will cause adjustments throughout the body. Luckily, most symptoms can be cleared up by drinking plenty of water, by replenishing your electrolytes, and by consuming mineral-rich, nutrient-dense foods.

For the vast majority of people who lose weight on the keto diet, their cholesterol levels will also improve. However, a small number of people may experience increased total cholesterol on a low-carb, high-fat diet. It is recommended that you check your cholesterol levels prior to starting keto, and checking them again 3-6 months later to see how they’re impacted. If your cholesterol increases, make sure to rule out any medical or genetic conditions that may cause high cholesterol levels. Monounsaturated fats ─ like those found in olive oil, avocados, and nuts ─ have cholesterol-lowering effects compared to saturated fats. Drinking unfiltered coffee can cause elevated cholesterol levels. The cholesterol spike is believed to be caused by oils called terpenes that are found in coffee, but are mostly removed by filters.

Yes! The ketogenic diet specifically impacts mechanisms responsible for excess, or chronic, inflammation. When the body starts burning fat instead of sugar, the body enters ketosis or a ketogenic state. These ketones in the body boast powerful anti-inflammation effects. Beta-hydroxybutyrate (BHB), present in ketogenic meals, is a strong anti-inflammatory, fending off inflammatory markers like NFkB and COX-2. BHB also activates the antioxidant pathways. BHB exerts pain and inflammation-relieving effects by keeping the COX-2 enzyme in check.

The ketogenic diet is easy for some to follow, and challenging for others. It depends on various factors, such as how well you prepare for it, and how strongly addicted to carbs you are when you start. For those who love carbs, giving them up and resisting temptation can be especially challenging. Plus, those who are used to eating a lot of carbs and processed foods are more likely to feel symptoms of the Keto Flu as their body transitions to using fat for fuel. Others find it easy to stick to the keto-approved food list and just say goodbye to carbs cold turkey. As with all diets, the level of discipline varies by individual. What is true for most people is that if you stick with keto and get through the initial transition, most people report enhanced energy, improved mental clarity, and various health benefits (e.g. weight loss, better sleep, improved metabolic markers, etc.) The ketogenic diet works best when you treat it as a permanent lifestyle as opposed to a temporary diet.  

The keto diet is good for many athletes. Many endurance athletes turn to low-carb, high-fat diets to boost their performance. In fact, endurance athletes ─ such as marathon runners and long-distance cyclists ─ might even fare better on a ketogenic diet than athletes who use short bursts of energy. Recreational athletes tend to see more consistent benefits from adopting a ketogenic diet because, on average, they have a greater emphasis on weight loss, metabolic, and health benefits.


BHB stands for beta-hydroxybutyrate. It’s a source of exogenous ketones and is taken to enhance ketone production, which can support a state of ketosis.

MCTs stand for medium-chain triglycerides. They are found in certain ingredients such as coconut, butter, and MCT oil. MCTs are a source of fuel for the brain and body while in ketosis because they are easily digestible and efficiently converted to ketones.


Caregivers and patients can purchase trumacro products from select doctors and medical institutions or directly from trumacro after medical consent has been received.

The Orphan Drug Act of 1988 defines a medical food as “a food which is formulated to be consumed or administered enterally (or orally) under the supervision of a physician and which is intended for the specific dietary management of a disease or condition for which distinctive nutritional requirements, based on recognized scientific principles, are established by medical evaluation.”Medical foods are specially formulated foods intended for the dietary management of certain medical conditions with distinctive nutritional requirements, which cannot be managed by altering a normal diet. The term “medical food” does not include all foods recommended by a physician, or fed to sick patients. Medical foods must be uniquely formulated for particular dietary conditions created by certain diseases. Medical foods must be used under the supervision of a physician. Medical food must comply with Good Manufacturing Practice regulations and adhere to labeling practices for protection against major food allergens.